Advancing the Future of Real-World Evidence: REALM at the MetReal Multistakeholder Workshop

2–3 March 2026 | Copenhagen

REALM participated in the MetReal Multistakeholder Meeting organised by the REDDIE project and hosted by the Danish Medicines Agency in Copenhagen. The two-day workshop brought together the MetReal Cluster projects, regulators, HTA bodies, industry representatives and other key stakeholders to strengthen collaboration on real-world evidence (RWE) in Europe.

The MetReal cluster combines REDDIE, More- EUROPA, ONCOVALUE, Real4Reg, INSAFEDARE and the REALM project, with the aim to explore innovative approaches to leverage real-world and synthetic data for regulatory decision-making and HTA.

Across discussions, one message stood out clearly: Europe hosts many strong RWE initiatives, but greater alignment and communication across projects are essential to maximise impact in regulatory and HTA decision-making.

Gökhan Ertaylan from VITO and Janaki Raman Rangarajan from VPH Institute attended the workshop as REALM representatives. During the first day, Gökhan Ertaylan presented the project’s objectives and vision, highlighting REALM’s role in advancing methodological approaches and fostering capacity-building through the upcoming REALM Academy workshops. The REALM Academy serves as a platform to support knowledge-sharing and strengthen expertise in RWE across stakeholder groups.

On the second day, participants engaged in forward-looking breakout discussions. Contributions focused on identifying what evidence is most valuable for HTA and regulatory decisions and exploring what future EU RWE projects should prioritise to ensure meaningful impact.

The workshop discussions reinforced REALM’s commitment to collaboration within the MetReal Cluster and beyond. By joining forces with complementary initiatives, we can shape a more coherent, transparent and impactful European real-world evidence ecosystem.